So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. The gulf between biology and the physical sciences is finally becoming bridged. This new edition includes an Epilogue describing developments in the concepts of fundamental forms of stability discussed in the book, and their profound implications.
Oxford landmark science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think. Strikingly, he demonstrates that darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle.
Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. Oxford university Press, USA. Seventy years ago, erwin schrodinger posed a profound question: 'What is life, and how did it emerge from non-life?' This problem has puzzled biologists and physical scientists ever since.
Addy pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life.
What is Life?: With Mind and Matter and Autobiographical Sketches Canto Classics
It was written for the layman, but proved to be one of the spurs to the birth of molecular biology and the subsequent discovery of DNA. Brought together with these two classics are Schrödinger's autobiographical sketches, which offer a fascinating account of his life as a background to his scientific writings.
What is life? appears here together with Mind and Matter, his essay investigating a relationship which has eluded and puzzled philosophers since the earliest times. Cambridge University Press. Nobel laureate erwin schrödinger's What is Life? is one of the great science classics of the twentieth century.
The Vital Question: Energy, Evolution, and the Origins of Complex Life
One of the deepest, most illuminating books about the history of life to have been published in recent years. The economistthe earth teems with life: in its oceans, forests, skies and cities. Then, on just one occasion in four billion years, they made the jump to complexity. How and why did this radical transformation happen?The answer, Lane argues, lies in energy: all life on Earth lives off a voltage with the strength of a lightning bolt.
We do not know why complex life is the way it is, for that matter, or, how life first began. Building on the pillars of evolutionary theory, lane’s hypothesis draws on cutting-edge research into the link between energy and cell biology, in order to deliver a compelling account of evolution from the very origins of life to the emergence of multicellular organisms, while offering deep insights into our own lives and deaths.
Both rigorous and enchanting, and indeed, the vital Question provides a solution to life’s vital question: why are we as we are, why are we here at all? 37 illlustrations Cambridge University Press. All complex life, shares puzzling features, such as sex, from mushrooms to man, which are unknown in bacteria.
W w norton Co Inc. Yet there’s a black hole at the heart of biology. In the vital question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.
Life's Ratchet: How Molecular Machines Extract Order from Chaos
Tiny electrical motors turn electrical voltage into motion, untwist, nanoscale factories custom-build other molecular machines, and mechanical machines twist, separate and package strands of DNA. Life is an enduring mystery. We are agglomerations of interacting nanoscale machines more amazing than anything in science fiction.
Hoffmann locates the answer to this age-old question at the nanoscale. Below the calm, ordered exterior of a living organism lies microscopic chaos, or what Hoffmann calls the molecular stormspecialized molecules immersed in a whirlwind of colliding water molecules. Basic Books. Yet, science tells us that living beings are merely sophisticated structures of lifeless molecules.
W w norton Co Inc. Rather than relying on some mysterious life force” to drive themas people believed for centurieslife's ratchets harness instead the second law of thermodynamics and the disorder of the molecular storm. Grounded in hoffmann's own cutting-edge research, Life's Ratchet reveals the incredible findings of modern nanotechnology to tell the story of how the noisy world of atoms gives rise to life itself.
Cambridge University Press. The cell is like a cityan unfathomable, complex collection of molecular workers working together to create something greater than themselves. Life, hoffman argues, emerges from the random motions of atoms filtered through these sophisticated structures of our evolved machinery.
Oxygen: The molecule that made the world Oxford Landmark Science
Giant spiders, tree-ferns, marine rock formations and fossil charcoalsall tell the same story. The book explains far more than the size ofancient insects: it shows how oxygen underpins the origin of biological complexity, the sudden evolution of animals, the accelerated ageing of cloned animals like Dolly the sheep, the birth of photosynthesis, the need for two sexes, and the surprisingly long lives of bats and birds.
Drawing on this grand evolutionary canvas, why we age, explaining modern killer diseases, Oxygen offers fresh perspectives on our own lives and deaths, and what we can do about it. Three hundred million years ago, in Carboniferous times, dragonflies grew as big as seagulls, with wingspans ofnearly a metre.
Oxygen is a toxic gas. Fruit flies raised at twice normal atmospheric levels of oxygen live half as long as theirsiblings. This remarkable book might just redefine the way we think about the world. Oxford landmark science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.
Reactive forms of oxygen, known as free radicals, are thought to cause ageing in people. Yet ifatmospheric oxygen reached 35 per cent in the carboniferous, as gripping as a thriller, instead of rapid ageing and death? Oxygen takes the reader on an enthralling journey, why did it promote exuberant growth, as it unravels the unexpectedways in which oxygen spurred the evolution of life and death.
High oxygen levels may also explain the global firestorm that contributed to thedemise of the dinosaurs after the asteroid impact. Oxygen has had extraordinary effects on life.
The Story of the Human Body: Evolution, Health, and Disease
In this landmark book of popular science, Daniel E. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes even compel us to create a more salubrious environment and pursue better lifestyles. With charts and line drawings throughout. Cambridge University Press.
He illuminates the major transformations that contributed to key adaptations to the body: the rise of bipedalism; the shift to a non-fruit-based diet; the advent of hunting and gathering; and how cultural changes like the Agricultural and Industrial Revolutions have impacted us physically. Basic Books. He shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning a paradox: greater longevity but increased chronic disease.
Lieberman gives us a lucid and engaging account of how the human body evolved over millions of years. Vintage Books. W w norton Co Inc. Oxford university Press USA.
Your Inner Fish: A Journey into the 3.5-Billion-Year History of the Human Body
Vintage Books. Basic Books. Cambridge University Press. Oxford university Press USA. By examining fossils and dna, our heads are organized like long-extinct jawless fish, he shows us that our hands actually resemble fish fins, and major parts of our genomes look and function like those of worms and bacteria.
Vintage. Your inner fish makes us look at ourselves and our world in an illuminating new light. W w norton Co Inc. This is science writing at its finest—enlightening, accessible and told with irresistible enthusiasm. The basis for the PBS series. Neil shubin, the paleontologist and professor of anatomy who co-discovered Tiktaalik, the “fish with hands, ” tells the story of our bodies as you've never heard it before.
Neanderthals Rediscovered: How Modern Science Is Rewriting Their Story Revised and Updated Edition
Oxford university Press USA. W w norton Co Inc. Morse compile the first full chronological narrative of the Neanderthals’ dramatic existence―from their evolution in Europe to their expansion to Siberia, cult movies, their subsequent extinction, and ultimately their revival in popular novels, cartoons, and television commercials.
It turns out that the neanderthals’ behavior was surprisingly modern: they buried the dead, hunted large animals in their prime, cared for the sick, harvested seafood, and communicated with spoken language.77 illustrations, 20 in color Cambridge University Press. In this important volume, Dimitra Papagianni and Michael A.
Vintage. Meanwhile, advances in dnA technologies are compelling us to reassess the Neanderthals’ place in our own past. Vintage Books. For hundreds of thousands of years, and, neanderthals evolved in Europe parallel to Homo sapiens evolving in Africa, when both species made their first forays into Asia, the Neanderthals may even have had the upper hand.
. Thames Hudson. Basic Books. In the first complete chronological narrative of the species from emergence to extinction.
Life on the Edge: The Coming of Age of Quantum Biology
Life remains the only way to make life. Thames Hudson. W w norton Co Inc. Broadway Books. Vintage. New york times bestseller • life on the Edge alters our understanding of our world's fundamental dynamics through the use of quantum mechanics. Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: nobody has ever made anything living entirely out of dead material.
. Basic Books. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge illustrates one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe.
Guiding the reader through the rapidly unfolding discoveries of the last few years, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, Al-Khalili and McFadden describe the explosive new field of quantum biology and its potentially revolutionary applications, life exists on the quantum edge.
Winner, stephen hawking Medal for Science Communication Cambridge University Press. Are we still missing a vital ingredient in its creation? Using first-hand experience at the cutting edge of science, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics. Vintage Books.
Oxford university Press USA.
The Machinery of Life
But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. An x-ray microscope would do the trick, perhaps an Asimov-style nanosubmarine unfortunately, or since we’re dreaming, neither is currently feasible.
Vintage. Vintage Books. Imagine that we had some way to look directly at the molecules in a living organism. Thames Hudson. Broadway Books. Cambridge University Press. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, and comput- generated pictures, showing the arrangement of molecules inside, which show the atomic details of individual molecules.
. Basic Books. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. Oxford university Press USA. In this second edition of the machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition.
Many of the questions puzzling the current cadre of sci- tists would be answered at a glance.
Gene Machine: The Race to Decipher the Secrets of the Ribosome
Thames Hudson. Basic Books. W w norton Co Inc. Cambridge University Press. But this is also a human story of ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. Vintage Books. A nobel prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end.
Siddhartha mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Vintage. Broadway Books. But by itself, DNA is just an inert blueprint for life.
In the end, gene machine is a frank insider's account of the pursuit of high-stakes science. Oxford university Press USA. Gene machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.